課程資訊
課程名稱
 生醫物理
Physics for Medicine and Biology 
開課學期
 102-2 
授課對象
 工學院  醫學工程學研究所  
授課教師
 林文澧 
課號
 Biomed7052 
課程識別碼
 548 M0870 
班次
  
學分
 3 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期五6,7,8(13:20~16:20) 
上課地點
  
備註
 教室：基醫503。
總人數上限：30人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1022Biomed7052_ 
課程簡介影片
 
核心能力關聯
 核心能力與課程規劃關聯圖
課程大綱
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課程概述

1.Biomechanics： Equilibrium, forces on hip, stress and strain, hydrostatics, viscosity and viscous flow, etc.
2.Exponential growth and decay：Exponential growth and decay
3.System of many particles：Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy, etc.
4.Transport in an infinite medium：Flux, continuity, solvent drag, diffusion, etc.
5.Transport through neutral membranes：Membrane, osmotic press, solute transport, artificial kidney, etc.
6.Impulses in nerve and muscle cell：Properties of nerves, electric field, charge distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model, propagation, etc.
7.The exterior potential and the electrocardiogram：The exterior potential and the electrocardiogram
8.Biomagnetism：Biomagnetism
9.Electricity and magnetism at the cellular level：Electricity and magnetism at the cellular level
10.Biofeedback：Biofeedback

持續改善：因應每屆修課學生背景不同而調整授課內容或難易度  

課程目標
 以微觀的觀點探討生物的一些物理特性 
課程要求
 期未報告：
一人交一份期未報告
於期未前兩週公佈相關題目
依題目要求尋找三至五篇相關paper
整理成一份書面報告及簡報檔
並於學期未上台做十五~二十分鐘的內容報告。
 
預期每週課後學習時數
  
Office Hours
 另約時間 
指定閱讀
 無 
參考書目
 1.Intermediate Physics for Medicine and Biology, 3rd Edition, Hobbie RK, AIP Press, 1997.
2.The physical basis of Biochemistry: The Foundations of Molecular Biophysics, Bergethon PR, Springer-Verlag, 1998. 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
第1週
 2/21  生醫物理課程大綱 
第2週
 2/28  228紀念日 停課一次 
第3週
 3/07  2.System of many particles: microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, equilibrium, Gibbs free energy, etc.[核心能力：2、4] 
第4週
 3/14  2.System of many particles: microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, equilibrium, Gibbs free energy, etc.[核心能力：2、4] 
第5週
 3/21  2.System of many particles: microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, equilibrium, Gibbs free energy, etc.
3.Transport in an infinite medium:flux, continuity, solvent drag, diffusion, steady-state diffusion to a spherical cell and end effects, drift and diffusion in 1-D, etc.[核心能力：2、4]  
第6週
 3/28  3.Transport in an infinite medium:flux, continuity, solvent drag, diffusion, steady-state diffusion to a spherical cell and end effects, drift and diffusion in 1-D, etc.[核心能力：2、4] 
第7週
 4/04  民族掃墓節 停課一次 
第8週
 4/11  3.Transport in an infinite medium:flux, continuity, solvent drag, diffusion, steady-state diffusion to a spherical cell and end effects, drift and diffusion in 1-D, etc.
4.Transport through neutral membranes:Menbrane, osmotic pressure, solute transport, artificial kidney, countercurrent transport, volume and solute transport in a pore, etc.[核心能力：2、4]  
第9週
 4/18  4.Transport through neutral membranes:Menbrane, osmotic pressure, solute transport, artificial kidney, countercurrent transport, volume and solute transport in a pore, etc.[核心能力：2、4]  
第10週
 4/25  4.Transport through neutral membranes:Menbrane, osmotic pressure, solute transport, artificial kidney, countercurrent transport, volume and solute transport in a pore, etc.
5.Impulses in nerve and muscle cells:Properties of nerves, electric field, charged distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model for membrane current, propagation of nerve impulse, rhythmic electrical activity, etc.[核心能力：2、4]  
第11週
 5/02  5.Impulses in nerve and muscle cells:Properties of nerves, electric field, charged distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model for membrane current, propagation of nerve impulse, rhythmic electrical activity, etc.
6.Exterior potential and Electrocardiogram(ECG):Potential outside an axon, exterior potential for a pulse, ECG, electrical stimulation, electroencephalogram(EEG),etc.[核心能力：2、4]  
第12週
 5/09  6.Exterior potential and Electrocardiogram(ECG):Potential outside an axon, exterior potential for a pulse, ECG, electrical stimulation, electroencephalogram(EEG),etc.[核心能力：2、4] 
第13週
 5/16  7.Biomagnetism: Magnetic field around an axon, magnetocardigram(MCG), magnetoencephalogram(MEG), magnetic stimulation, etc.[核心能力：2、4]  
第14週
 5/23  Exam.[核心能力：2、4] 
第15週
 5/30  8.Electricity and magnetism at the cellular level:Donnan equilibrium, ion movement in solution, membrane channels, sensory transducers, possible effects of weak external electrical and magnetic fields, etc.[核心能力：2、4] 
第16週
 6/06  8.Electricity and magnetism at the cellular level:Donnan equilibrium, ion movement in solution, membrane channels, sensory transducers, possible effects of weak external electrical and magnetic fields, etc.
9.Biofeedback and control:Feedback loop with time constants, difference equations and chaotic behavior, feedback loop with a fixed delay,etc.[核心能力：2、4]  
第17週
 6/13  Presentation and Report[核心能力：2、4] 
第18-1週
 6/20  Presentation and Report[核心能力：2、4] 
第18-2週
 6/20  生醫物理考試抽存，課程期末問卷 修課人數= 19 ，問卷回收率=84.2%